The composition unfolds in two registers. Above, the Virgin emerges among clouds with the Christ Child in her arms. Below, a mountainous landscape contains a man and a woman whose clothing places them within an Indigenous Andean setting.

The man wears an unku and a hat, while the woman's mantle, or lliclla, is fastened with a decorative tupu. These details give local specificity to a Marian devotion that extended throughout the Spanish-speaking world.

A surviving inscription identifies the subject as the Mother of God of the Remedies, although its fragmentary condition prevents a secure identification of the figures or the original patronage. The catalogue of El Manto de los Pueblos places the painting in Cusco around 1800 and proposes Antonio Vilca or Cipriano de Toledo Gutiérrez as possible authors.